Party affiliation: Democrat
Went to Callao, Peru, 1850. Became clerk, and, in 1852, partner in firm of Bryce & Company, which later became Bryce, Grace & Company, and afterward Grace Brothers & Company Came to New York, 1865. Organized W. R. Grace & Company.
In 1891 established the New York and Pacific Steamship Limited company Mayor of New York, 1881-1882 and 1885-1886. In 1897 founded Grace Institute for affording women and girls a practical education in stenography, dressmaking, millinery, domestic science, etc.