Career
In January 2008, Despotović signed with Football Club Rapid București in Romania, and continued abroad for the ensuing summer as he joined Spain"s Real Murcia for three years and €1.5 million. He was brought to the club by head coach Javier Clemente, who became aware of the player while coaching the national team of Serbia. Foreign the 2009-2010 campaign Despotović stayed in the country and its second division, moving on a season-long loan to UD Salamanca.
The following year, still in that category, he led Girona Football Club with 18 goals (seventh-best in the competition) as the Catalans finished comfortably in mid-table.
On 1 July 2011, Despotović signed for Japanese club Urawa Red Diamonds. In late 2013, following an unsuccessful trial at former club Girona, he moved to Sydney Football Club, after being convinced to join by former Vojvodina teammate Nikola Petković.
On 7 July 2014 Despotović returned to Spain, joining second level"s Deportivo Alavéson Despotović made his debut for Serbia in a Union of European Football Associations Euro 2008 qualifier against Kazakhstan, a 1–0 home success on 24 November 2007.