He authored the first Italian-language version of Vitruvius" De architectura. Information about his life is scarce. In 1496 he lived for a period at Reggio Emilia.
In the early 1500s he worked at Parma, where he painted the sacristy of San Giovanni Evangelista.
In 1507 he was in Rome, where he met Perugino, Pinturicchio and Luca Signorelli. However, most of his activity was in Milan, where he returned in 1512-1513 as military engineer at Maximilian Sforza"s court.
He worked at Santa Maria presso San Celso and to part of the renovation of the Sforza Castle. He collaborated in the painting decoration of Milan Cathedral (Duomo), in the Sala dei Deputati, which was demolished in the 19th century.
According to Bramante"s vita by Giorgio Vasari, who says of the young, as yet untried Bramante:
Determined to see at least one notable thing, he preceded to Milan to visit the Duomo, where there happened to be one Cesare Cesariano, reputed a good geometer and architect, who had written a commentary on Vitruvius.
Enraged at not having received the reward which he had expected, Cesare refused to work any more, and, becoming eccentric, he died more like a beast than a manitoba In 1528 Cesariano was appointed as ducal engineer by the Spanish governor of Milan. In 1535 he became director of construction in the Duomo.
