Background
His father was from city of Shkodra, in the north of Albania, and his mother was from Vlora, in the south of Albania.
Grand Vizier of the Ottoman Empire
His father was from city of Shkodra, in the north of Albania, and his mother was from Vlora, in the south of Albania.
He was an Albanian born in Himare region. He was taken to Istambul under the Devşirme practice, and was trained to serve as an aga with the janissaries. He participated in the Battle of Chaldiran (1514), and Ottoman–Mamluk War (1516-1517).
During 1520–1521 he was beylerbey of Anatolia and governor of Damascus.
During the reign of Suleiman the Magnificent, he served as beylerbey of Roumelia and was made a vizier after the Ottoman conquest of Rhodes in 1522. He also participated in the Battle of Mohács, Siege of Vienna, and the war in Iraq (1534–1535).
He became grand vizier in 1536 after the execution of Pargali Ibrahim Pasha and kept this position until his death in 1539. Under his administration, the Ottomans undertook the Corfu campaign (1537) and waged war against the Habsburgs in Vienna (1537–1540).
Additionally, his native Vlore region was put under full Ottoman control, and the Sandjak of Delvina was created.
He died of plague in Istanbul and was buried in the Eyüp Sultan Mosque. In the television series Muhteşem Yüzyıl, Ayas Mehmed Pasha is played by Turkish actor Fehmi Karaarslan.