Background
Henderson was born in Auckland, New Zealand.
"Bride and Prejudice", 2008
Henderson was born in Auckland, New Zealand.
Henderson starred in the drama Shortland Street, where he played the character of "Stuart Neilson" from 1992 to 1995. He subsequently appeared in a number of Australian films and television productions Echo Point and Home & Away before he moved to the United States in 1997, in order to pursue a career in Hollywood films and to train in a two-year program at the Neighborhood Playhouse in New York City.
Henderson spent more than a year unsuccessfully auditioning for film roles in Los Angeles, but in 2001, he was finally cast in a supporting role in the John Woo-directed war film, Windtalkers. In 1999 he appeared in a major leading role in Kick for which he was nominated by Australian Film Institute to "Best Performance by an Actor in a Supporting Role".
In 2002, he starred opposite actress Naomi Watts in the horror film, The Ring. Following the box office success of the film, Henderson received a role playing the character of Drew in Perfect Opposites, and subsequently was cast as the lead character in the biker film Torque, released in early 2004 to mixed reviews. In 2005, he starred opposite Indian actress Aishwarya Rai in the romantic film Bride & Prejudice, and in the award-winning Little Fish starring Cate Blanchett.
In 2006 Henderson won rave reviews in London's West End in a theatre production of Fool for Love with Juliette Lewis.
Henderson has also appeared alongside Britney Spears in the music video for her single "Toxic." He was set to star alongside Jordana Brewster in the television series adapted from the 2005 movie Mr. & Mrs. Smith. As of 2008, the series has not been picked up by any network. Recently, Henderson has appeared in a commercial for the 2008 Cadillac CTS, and the House episode "Painless". In 2010 it was announced Henderson had been cast in Grey's Anatomy creator Shonda Rhime's new television series Off the Map wherein doctors travel to the end of the world to rediscover why they had initially wanted to become doctors.