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George Hoyt Whipple Edit Profile

pathologist , Physician , medical educator , biomedical researcher

George Hoyt Whipple was an American physician, pathologist, biomedical researcher, and medical school educator and administrator.

Background

Whipple was born on August 28, 1878 to Ashley Cooper Whipple and Frances Anna Hoyt in Ashland, New Hampshire. He was the son and grandson of physicians.

Education

He attended local schools until, at age 13, he transferred to a school in Tilton 15 miles away.

Then in 1892 his widowed mother moved to Andover, Massachusetts, so that George could attend Phillips Academy.

He received his A. B. degree from Yale University in 1900 and his M. D. degree from Johns Hopkins University in 1905.

Career

In 1918, Whipple began his studies of the effects of foods on the regeneration of blood cells and hemoglobin.

In 1920 Whipple was appointed dean of the University of California Medical School.

The anemic dogs were then fed various diets.

At Rochester, he extended his studies to the severe anemias.

The researches of Whipple and his colleagues on bile pigments and hemoglobin regeneration continued and were reported in a long series of scientific articles.

This discovery paved the way for the use of a raw liver diet in the treatment of pernicious anemia by George Richards Minot and William Parry Murphy.

He fed anemic dogs various diets, and then measured quantitatively their formation of new hemoglobin.

From these values, Whipple determined how much of each food was needed to regenerate a given amount of hemoglobin.

He found that liver and other iron-containing foods were the best dietary sources for restoring blood.

Murphy and Minot later applied Whipple's findings to the treatment of pernicious anemia in man.

He retired as dean in 1953 and as professor of pathology in 1955.

Whipple served the School as the Dean until 1954 and remained at Rochester for the rest of his life.

Whipple died in 1976 at the age of 97 and is interred in Rochester's Mount Hope Cemetery.

Achievements

  • The American pathologist George Hoyt Whipple found that certain foods, especially liver, stimulate the regeneration of hemoglobin in animals suffering anemia.

    Whipple was also the first person to describe an unknown disease he called lipodystrophia intestinalis because there were abnormal lipid deposits in the small intestine wall.

    Whipple also correctly pointed to the bacterial cause of the disease in his original report in 1907.

    The condition has since come to be called Whipple's disease.

    Whipple was a Professor and Chairman of Pathology and the founding Dean of the new School of Medicine and Dentistry at the University of Rochester.

    Whipple shared the Nobel Prize in Physiology or Medicine in 1934 with George Richards Minot and William Parry Murphy "for their discoveries concerning liver therapy in cases of anemia, " making Whipple the only Nobel laureate born in New Hampshire.

Personality

He was remembered as a superb teacher.

Connections

On June 24, 1914, Whipple married Katharine Ball Waring.

father:
Ashley Cooper Whipple

mother:
Frances Anna Hoyt

wife:
Katharine Ball Waring

friend:
Allen Whipple