Of Belarusian ancestry: Lisa's grandmother on her father's side, Grunia “Gertrude” Farberman, emigrated from the village of Ilya, Vileyka area, Minsk region. Lisa's great-grandmother, Mera Mordechowicz, was a Holocaust victim. The actress publicly acknowledges her ancestry and even paid a visit to her ancestors' land during the run of the show "Who Do You Think You Are?" in 2010.
Lisa Kudrow was born in the prestigious Encino neighborhood in the San Fernando Valley, Los Angeles, California. Her parents are Nedra Stern, a travel agent, and Dr. Lee N. Kudrow (b.1933), a doctor. She has an older sister, Helene Marla (b.1955), and an older brother, neurologist David B. Kudrow (b.1957).
Kudrow was raised in a middle-class Jewish family of Belarusian, German and Hungarian ancestry, and had a Bat Mitzvah coming-of-age ceremony. Her paternal great-grandmother, Mera Mordejovich, was murdered during the Holocaust; LIsa's paternal grandmother, Grunya "Gertrude" Farberman, was born in the village of Ilya, Vileyka area, Minsk region, and immigrated to Brooklyn, where her father Lee grew up.