She was educated at Ashley Hall in Charleston. She graduated from Vassar College with a Bachelor of Arts in history in 1957.
She serves as the chairman of Industries. Upon graduation, she found employment at WCSC-Department of Administration and Management/FM and WCSC-television, a radio and television station, respectively, owned by her father. After her husband"s death in 1995, she became Chairman of the Board and Chief Executive Officer.
She has ranked 524th on the Forbes list of richest people.
In 2015, donated to Republican candidate David Fox"s failed campaign to become the new Mayor of Nashville. She formerly served as Chairman of the Board of Trust of Vanderbilt University in Nashville.
The Vanderbilt Blair School of Music has been the recipient of $300 million of company stock. was honored by Business Week as the 50th most generous philanthropist for her donations between the years 2000 and 2004. In 2006 she was honored by the Community Foundation of Middle Tennessee as the 2006 recipient of the 13th Annual Joe Kraft Humanitarian Award for her philanthropic efforts.
Chairman Tennessee Bicentennial Commission, 1996. Board directors Tennessee Performing Arts Center, Nashville Ballet, Nashville Opera, Nashville Institute for Arts, Nashville Symphony, Nashville Community Foundation. Past chairman United Way's Alexis de Tocqueville Society.
Founder, board directors Tennessee Repertory Theater. Chairman board trustees Vanderbilt University, since 1999. Co-founder Ingram Charitable Fund, 1995.
Member Nashville Area Chamber of Commerce.
Married E. Bronson Ingram (deceased 1995), October 4, 1958. Children: Orrin Henry III, John Rivers, David Bronson, Robin.