Background
Brown, Adrian J. was born on April 27, 1852 in Burton-on-Trent. Son of Edwin Brown, Fellow of the Geological Society, Burton-on-Trent.
Brown, Adrian J. was born on April 27, 1852 in Burton-on-Trent. Son of Edwin Brown, Fellow of the Geological Society, Burton-on-Trent.
He attended the local grammar school and then went up to study chemistry at the Royal College of Science in London.
He became private assistant to Doctor Russell at Street Bartholomew"s Hospital Medical School. In 1873 he returned to Burton to work as a chemist in the brewing industry for the next twenty-five years. In 1899 he left to become Professor of Brewing and Malting at Mason University College (which became Birmingham University in 1900).
He studied the rate of fermentation of sucrose by yeast and suggested in 1892 that a substance in the yeast might be responsible for speeding up the reaction.
This was the first time enzymes were suggested as separate entities from organisms and talked about in chemical terms. He later studied the enzyme responsible and made the striking suggestion that the kinetics he observed were the result of an enzyme-substrate complex being formed during the reaction, a concept that has formed the basis of all later work on enzyme kinetics.
(Excerpt from Laboratory Studies for Brewing Students: A S...)
(High Quality Facsimile Reporduction: Brown, Adrian J :Lab...)
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Fellow of Institute of Chemistry. Club: Union, Birmingham.