Alexander Jacob Varshavsky Edit Profile

Background

Varshavsky, Alexander Jacob was born on November 8, 1946 in Moscow. Son of Jacob M. and Mary B. (Zeitlin) Varshavsky. came to the United States, 1977.

Education

Bachelor of Science in Chemistry, Moscow State University, 1970; Doctor of Philosophy in Biochemistry, Institute of Molecular Biology, Moscow, 1973.

Career

A native of Moscow, he is currently researching at Caltech. Varshavsky provided an original approach to killing cancer cells, proffering the idea of a targeted molecular device that could enter a cell, examine it for deoxyribonucleic acid deletions specific to cancer and killing it if it meets the right profile. "(lieutenant) involves, in a nutshell, the finding of a genuine Achilles" heel of cancer cells, id est (that is) their potentially vulnerable feature that won"t change during tumor progression," said Varshavsky.

The approach termed deletion-specific targeting (Department of Science and Technology), employs HDs (homozygous deoxyribonucleic acid deletions) as the targets of cancer therapy.

"In contrast to other attributes of cancer cells, their HDs are immutable markers. If the Department of Science and Technology strategy can be implemented in a clinical setting, it may prove to be both curative and free of side effects.".

Achievements

Alexander Jacob Varshavsky has been listed as a noteworthy molecular biologist, educator by Marquis Who's Who.

Membership

Fellow: American Association for the Advancement of Science, American Academy Arts & Sciences, American Academy Microbiology. Member: National Academy of Sciences, Academy Europaea, European Molecular Biology Organization, American Philosophical Society.

Connections

Married Vera Bingham, August 30, 1990. Children: Roman, Anna, Victoria.

Father:: Jacob M. Varshavsky
Mother:: Mary B. (Zeitlin) Varshavsky
Spouse:: Vera Bingham
child:: Anna Varshavsky
child:: Victoria Varshavsky
child:: Roman Varshavsky

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Born

November 8, 1946

Moscow, Russia
Nationality
United States
Ethnicity

Slavic

Education

1970

Moscow State University , Bachelor of Science in chemistry
1973

Moscow Institute Molecular Biology , Doctor of Philosophy in biochemistry

Career

Awards

Breakthrough Prize in Life Sciences; Albert Lasker Award for Basic Medical Research; Wolf Prize in Medicine; Gairdner Foundation International Award Louisa Gross Horwitz Prize; the Vilcek Prize; Gairdner Foundation International Award; March of Dimes Prize in Developmental Biology; Knowledge Award; Albany Medical Center Prize; Lasker Award; Wolf Prize in Medicine; Breakthrough Prize in Life Sciences; Massry Prize Recipient of the Gairdner Foundation International Award in 1999, Albert Lasker Award for Basic Medical Research in 2000, the Wolf Prize in Medicine, the Massry Prize from the Keck School of Medicine, University of Southern California in 2001, and the Louisa Gross Horwitz Prize from Columbia University in 2001 for his research on ubiquitination. In 2006 he won the March of Dimes Prize in Developmental Biology, and he won the 2007 $1 million Gotham Prize for an original approach to killing cancer cells. In 2010, he received the Vilcek Prize in Biomedical Science. The following year, he received the BBVA Foundation Frontiers of Knowledge Award of Biomedicine for his discovery of the mechanisms intervening in protein degradation and their importance in biological systems. His work has implications for the understanding of cancer and immunological and neurodegenerative diseases. In 2014 he was awarded the $3 million Breakthrough Prize in Life Sciences for his work and also the Albany Medical Center Prize. The Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by Columbia University to a researcher or group of researchers who have made an outstanding contribution in basic research in the fields of biology or biochemistry.; The Wolf Prize in Medicine is awarded once a year by the Wolf Foundation in Israel.; The Lasker have been awarded annually since 1945 to living persons who have made major contributions to medical science or who have performed public service on behalf of medicine.; The March of Dimes Prize in Developmental Biology is awarded once a year by the March of Dimes.; The Breakthrough Prize in Life Sciences is a monetary award, funded by internet entrepreneurs: Mark Zuckerberg and Priscilla Chan of Facebook; Sergey Brin of Google; entrepreneur and venture capitalist Yuri Milner; and Anne Wojcicki, one of the founders of the genetics company 23andMe.; The Massry Prize was established in 1996, and until 2009 was administered by the Meira and Shaul G. Massry Foundation.; The Albany Medical Center Prize in Medicine and Biomedical Research is the United States' second highest value prize in medicine and biomedical research, awarded by the Albany Medical Center.

Breakthrough Prize in Life Sciences; Albert Lasker Award for Basic Medical Research; Wolf Prize in Medicine; Gairdner Foundation International Award Louisa Gross Horwitz Prize; the Vilcek Prize; Gairdner Foundation International Award; March of Dimes Prize in Developmental Biology; Knowledge Award; Albany Medical Center Prize; Lasker Award; Wolf Prize in Medicine; Breakthrough Prize in Life Sciences; Massry Prize Recipient of the Gairdner Foundation International Award in 1999, Albert Lasker Award for Basic Medical Research in 2000, the Wolf Prize in Medicine, the Massry Prize from the Keck School of Medicine, University of Southern California in 2001, and the Louisa Gross Horwitz Prize from Columbia University in 2001 for his research on ubiquitination. In 2006 he won the March of Dimes Prize in Developmental Biology, and he won the 2007 $1 million Gotham Prize for an original approach to killing cancer cells. In 2010, he received the Vilcek Prize in Biomedical Science. The following year, he received the BBVA Foundation Frontiers of Knowledge Award of Biomedicine for his discovery of the mechanisms intervening in protein degradation and their importance in biological systems. His work has implications for the understanding of cancer and immunological and neurodegenerative diseases. In 2014 he was awarded the $3 million Breakthrough Prize in Life Sciences for his work and also the Albany Medical Center Prize. The Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by Columbia University to a researcher or group of researchers who have made an outstanding contribution in basic research in the fields of biology or biochemistry.; The Wolf Prize in Medicine is awarded once a year by the Wolf Foundation in Israel.; The Lasker have been awarded annually since 1945 to living persons who have made major contributions to medical science or who have performed public service on behalf of medicine.; The March of Dimes Prize in Developmental Biology is awarded once a year by the March of Dimes.; The Breakthrough Prize in Life Sciences is a monetary award, funded by internet entrepreneurs: Mark Zuckerberg and Priscilla Chan of Facebook; Sergey Brin of Google; entrepreneur and venture capitalist Yuri Milner; and Anne Wojcicki, one of the founders of the genetics company 23andMe.; The Massry Prize was established in 1996, and until 2009 was administered by the Meira and Shaul G. Massry Foundation.; The Albany Medical Center Prize in Medicine and Biomedical Research is the United States' second highest value prize in medicine and biomedical research, awarded by the Albany Medical Center.

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