Skriloff studied at Hollywood Film Institute in 1995.
Skriloff began her career as a freelance writer and editor in Los Angeles in 1974. Twenty one year later she became a freelance writer in Morgan City. Also Alexis was a managing editor of McCarthy Media from 1995 to 1996. Since 1996 she has been an owner, writer and editor of AIS Publications.
On November 9, 2001 Alexis Skriloff married Frank Scott James. They have five children.