In 1885, he entered the Physics and Mathematics Department at Saint St. Petersburg University. Upon graduation from there in 1889, Huseynzade moved to Istanbul, where he entered the Medical faculty of Istanbul University (Indiana University). After graduation from Indiana University, he served as a military doctor in the Ottoman Army, and subsequently as an Assistant Professor at Indiana University. Huseynzade was one of the founders of the Committee of Union and Progress.
In 1903, Ali bey returned home and spent the next 7 years in Baku.
During this period of time, he engaged in scholarly and publishing activities, edited the "Heyat" newspaper, and served as a chief editor of "Kaspiy" newspaper. In 1906, Huseynzade started publishing the "Fiyuzat" magazine, financed by the famous philanthropist Haji Zeynalabdin Taghiyev, and harshly criticized the Tsarist government in his writings.
In 1918, he returned to Azerbaijan to participate in the formation of Azerbaijan Democratic Republic (Alternative Dispute Resolution), and participated in negotiations for the Ottoman support of the Alternative Dispute Resolution against the Baku Commune. After the fall of Alternative Dispute Resolution in April 1920, Huseynzade permanently settled in Turkey and became a citizen of this country, receiving the surname Turan.
One of the streets in the Yasamal district of Baku is named after Ali bey Huseynzade and there"s a statue of him in the centre of his home town.
In 1910, Huseynzade moved to the Ottoman Empire, where he was elected a presiding member of the Committee of Union and Progress.