Background
Burlingame, Alma Lyman was born on April 29, 1937 in Cranston, Rhode Island, United States. Son of Herman Follett Junior and Rose Irene (Kohler) Burlingame.
(The methods, instrumentation, opportunities and present f...)
The methods, instrumentation, opportunities and present focus of international research efforts involving the study of proteins, glycoconjugates and nucleic acids use mass spectrometry as a primary structural strategy rather than as an auxiliary technique. Not only is there established interest in the metabolism of endogenous and xenobiotic substances, per se, but also in the fact that when particular structures are metabolized, they form reactive electrophilic intermediates which may covalently bind to macromolecules, and eventually become manifest in the cell or organism as toxicity or chemical carcinogenesis. Additional important covalent modifications involve studies of chemical and photoaffinity labeling of macromolecules, studies of substrate and large molecules (receptor, enzyme, etc.), binding sites, interactions and membrane topography. In this volume, the authors explore new methods of tandem mass spectrometry with array detection systems which provide high accuracy in identification, are far more rapid than the automated Edman sequencing devices, and have comparable sensitivity.
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Burlingame, Alma Lyman was born on April 29, 1937 in Cranston, Rhode Island, United States. Son of Herman Follett Junior and Rose Irene (Kohler) Burlingame.
Bachelor of Science, U. Rhode Island, 1959; Doctor of Philosophy, Massachusetts Institute of Technology, 1962.
Assistant professor, University of California, Berkeley, 1963-1968; associate chemist, University of California, Berkeley, 1968-1972; research chemist, University of California, Berkeley, 1972-1978; professor, University of California, San Francisco, since 1978; professor, University College, London, since 1996. Visiting professor Ludwig Institute for Cancer Research, London, 1993-1994.
(The methods, instrumentation, opportunities and present f...)
With United States Army Reserve, 1954-1962. Fellow American Association for the Advancement of Science.
Children: Mark, Walter. Married Marilyn F. Schwartz, February 14, 1993. 1 stepchild, Corey Schwartz.