Anna Rosina was born into a family of painters of Polish noble origin in Berlin. Her father, Georg Lisiewski (1674–1751), taught her painting and also taught her younger sister Anna Dorothea (1721–1782) and her brother Christoph Friedrich (1725–1794).
She later studied with the painter Antoine Pesne and learned his style of painting.
In 1757, she was appointed as court painter by Frederick Augustus of Anhalt-Zerbst. During her ten-year stay at the court, she painted a gallery of forty ladies. Later, she moved to the ducal court in Brunswick, where she received a generous grant from Duchess Philippine Charlotte of Brunswick-Wolfenbüttel.
In 1741, Anna Rosina married the Prussian court painter David Matthieu (1697–1755) and became the stepmother of Georg David Matthieu.
She had two children with him. Anna Rosina de Gasc died in 1783 in Dresden.
1757: Court painter in Anhalt-Zerbst.
1769: Honorary Member of the Dresden Academy of Fine Arts.
