Background
Born in Maidstone, England, the son of the cricketer and writer Tony Pawson, and botanist and high-school teacher Hilarie, he was the eldest of three children.
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Anthony Pawson
Edit Profileuniversity professor molecular biologist
Anthony "Tony" James Pawson, OC OOnt Companies of Honour Federal Reserve System FRSC, was a British-born Canadian scientist whose research has revolutionized the understanding of signal transduction, the molecular mechanisms by which cells respond to external cues, and how they communicate with each other.
Education
He was educated at Winchester College and Clare College, Cambridge where he received a Master of Arts in biochemistry followed by a Doctor of Philosophy from King"s College London in 1976.
Career
He identified the phosphotyrosine-binding Src homology 2 (SH2 domain) as the prototypic non-catalytic interaction module. SH2 domains serve as a model for a large family of protein modules that act together to control many aspects of cellular signaling. Since the discovery of SH2 domains, hundreds of different modules have been identified in many proteins.
From 1976 to 1980 he pursued postdoctoral work at the University of California, Berkeley.
From 1981 to 1985, he was Assistant Professor in microbiology at the University of British Columbia. Pawson was a Distinguished Investigator and former Director of Research at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital and Professor in the Department of Molecular Genetics at the University of Toronto both of which he joined in 1985.
Pawson died on August 7, 2013 of unspecified causes, at the age of 60. 1994 Gairdner Foundation International Award.
Achievements
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1994 Gairdner Foundation International Award 1994 Fellow of the Royal Society of London and the Royal Society of Canada 1995 Robert L. Noble Prize from the National Cancer Institute of Canada 1998 Pezcoller-American Association for Cancer Research International Award for Cancer Research 1998 Heineken Prize for Biochemistry and Biophysics, Royal Netherlands Academy of Arts and Sciences 1998 The Royal Society of Canada Flavelle Medal for meritorious achievement in biological science 2000 J. Allyn Taylor International Prize in Medicine 2004 Louisa Gross Horwitz Prize from Columbia University 2004 Poulsson Medal, the Norwegian Society of Pharmacology and Toxicology 2004 Associate of the National Academy of Sciences (United States) 2004 Member of the American Academy of Arts and Sciences 2005 Wolf Prize in Medicine "for his discovery of protein domains essential for mediating protein-protein interactions in cellular signaling pathways, and the insights this research has provided into cancer" 2005 The Royal Medal (The Queen"s Medal) from The Royal Society of London 2006 Companion of Honour 2007 Premiers Summit Award 2007 Howard Taylor Ricketts Award from University of Chicago 2008 Kyoto Prize - "Japan"s Nobel" for "Proposing and Proving the Concept of Adapter Molecules in the Signal Transduction" 2012 Thomson Reuters Citation Laureates, candidate for Nobel Prize in Medicine “for identification of the phosphotyrosine binding SH2 domain and demonstrating its function in protein-protein interactions”.
Membership
Royal Society; National Academy of Sciences.
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Born
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Died
August 7, 2013 (aged 60) -
Nationality
Canada United Kingdom
Awards
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Fellow of the Royal Society; Officer of the Order of Canada; Wolf Prize in Medicine; Royal Medal; Gairdner Foundation International Award Louisa Gross Horwitz Prize; Robert L. Noble Prize; Kyoto Prize; Arts and Sciences; Wolf Prize in Medicine; Queen's Medal The Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by Columbia University to a researcher or group of researchers who have made an outstanding contribution in basic research in the fields of biology or biochemistry.; The Kyoto Prize is Japan’s highest private award for global achievement.; The Wolf Prize in Medicine is awarded once a year by the Wolf Foundation in Israel.Fellow of the Royal Society; Officer of the Order of Canada; Wolf Prize in Medicine; Royal Medal; Gairdner Foundation International Award Louisa Gross Horwitz Prize; Robert L. Noble Prize; Kyoto Prize; Arts and Sciences; Wolf Prize in Medicine; Queen's Medal The Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by Columbia University to a researcher or group of researchers who have made an outstanding contribution in basic research in the fields of biology or biochemistry.; The Kyoto Prize is Japan’s highest private award for global achievement.; The Wolf Prize in Medicine is awarded once a year by the Wolf Foundation in Israel.