Life and Death Decision Making

(Integrating theory with realistic case studies, this book...)

Integrating theory with realistic case studies, this book examines the practical application of moral theory in clinical decision-making. With forty composite cases based on actual clinical experiences, the author describes key moral problems raised by modern medicine. He then demonstrates how these dilemmas can be resolved using a problem-solving framework termed pluralistic casuistry. This approach is pluralistic in that it accepts the relevance of many different moral grounds, drawn from different traditional moral theories, each of which may seem self-contained and hence in conflict with other claims. Consequently, the author stresses the need to achieve a synthesis of these traditional moral theories, rather than treating them as competitors. His approach is casuistrical in the sense that it considers the important differences between the cases at issue and applies the different moral appeals in different ways. The richly detailed case studies will challenge readers, clarify the ethical issues involved, and indicate how theory and practice can be integrated. Containing a multiplicity of factors faced in clinical crises, they are ideal for group discussions concerning the ways in which theory relates to actual life-or-death situations.

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Ethical Issues in Drug Testing, Approval, and Pricing: The Clot-Dissolving Drugs

(Although most developed countries have extensive regulati...)

Although most developed countries have extensive regulations governing the testing, approval and marketing of new drugs, there are major gaps in these regulations. In this compelling new volume, Dr. Brody uses the example of the development of thrombolytic drugs to identify several such gaps. Issues addressed include the use of placebo control groups in clinical trials, the importance of determining the type of consent that should be obtained for emergency research, and ways to avoid conflicts of interest in clinical trials. He also discusses topics such as deciding to continue clinical trials or to approve a drug quickly, maintaining a proper balance between efficacy and safety in drug approval, the pricing of new drugs and considering prices when ordering drugs. Dr. Brody offers a series of solutions based upon philosophical principles such as respect for individual differences in a liberal society. An insightful critique of the current process of approving drugs by the FDA in the United States is also provided. The book offers a new way to deal with questions about the cost of drugs. And it gives a complete history of a major medical development that saves thousands of lives each year, the use of clot-dissolving drugs for patients with heart attacks. This illuminating work offers the first comprehensive analysis from an ethical perspective of the entire drug development process, and it does so while comparing American and European approaches to the process.

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Life and Death Decision Making by Baruch A. Brody (1988-03-03)

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Identity and Essence (Princeton Legacy Library)

( Baruch Brody contends that the fundamental assumption o...)

Baruch Brody contends that the fundamental assumption on which the tradition is based is erroneous and that once this assumption is shown to be in error, all philosophical problems in this area have to be rethought. Originally published in 1980. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These paperback editions preserve the original texts of these important books while presenting them in durable paperback editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

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The Ethics of Biomedical Research: An International Perspective by Baruch A. Brody (1998-05-15)

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The Ethics of Biomedical Research: An International Perspective

(This book analyzes the major issues of research ethics th...)

This book analyzes the major issues of research ethics through a careful review of the treatment in official policies on research ethics developed throughout the world (especially North America, Western Europe, and the Pacific Rim). Among the issues covered are animal research, research on human subjects, epidemiological research, genetic research, reproductive research, research on vulnerable subjects, clinical trials, drug approval and the research process, and research on women and minorities. Brody also evaluates the content and the methods of developing these policies in light of his philosophical position of pluralistic casuistry. This is the only book that analyzes all the major issues in research ethics. It is the only book which deals with these issues from an international perspective rather than just a US perspective. Major official policies from important research-intensive countries are reprinted in the appendix (close to 200 plates of otherwise difficult material).

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Ethical Issues in Drug Testing, Approval, and Pricing: The Clot-Dissolving Drugs by Baruch A. Brody (1995-01-05)

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