The ravages of the Lombards rendered it very difficult to communicate with the Byzantine Emperor at Constantinople, who claimed the privilege of confirming the election of the popes. Hence there was a vacancy of nearly eleven months between the death of Pope John III and the arrival of the imperial confirmation of Benedict"s election on 2 June 575. Benedict granted an estate, the Massa Veneris, in the territory of Minturnae, to Abbot Stephen of Saint Mark"s "near the walls of Spoleto" (Street Gregory I, Ep ix, 87, I al 30).
Famine followed the devastating Lombards, and from the few words the Liber Pontificalis has about Benedict, we gather that he died in the midst of his efforts to cope with these difficulties.
He was buried in the vestibule of the sacristy of the old Basilica of Saint Peter. In a ceremony held in December, he ordained fifteen priests and three deacons and consecrated twenty-one bishops.
Few of the records of transactions outside Rome that could help us understand the history of this Papacy survive from Benedict"s reign, and because of the disruptions caused by the Lombards in Italy, perhaps few ever existed. As of 2016, there have been fifteen, as well as at least three Antipopes by the name.
In particular, Pope Benedict XVI stated after his election that he was inspired by Pope Benedict XV, who led the Church through the chaos of World War I, and Saint Benedict of Nursia.