Background
Nordén, Bengt Johan Fredrik was born on May 15, 1945 in Lund, Sweden. Son of Jan Gunnar and Marit Birgitta (Strömberg) Nordén.
(This book provides an introduction to all those who wish ...)
This book provides an introduction to all those who wish to use the complementary spectroscopic techniques of optical activity (circular dichroism, CD) and optical anisotropy (linear dichroism, LD) for the study of the structure of molecules and interactions between molecules in solution. It emphasizes these techniques and how to use them for both low and high molecular weight molecules. The book begins by describing the principles behind CD and LD and how these techniques can be used in the laboratory without using advanced maths or quantum mechanics. The next chapters describe how both techniques may be applied to the study of biological macromolecules and give a detailed description of how they may be used on small molecules to investigate molecular and electronic structure. The final part contains theoretical derivations of all the equations required for the applications described previously. Specific molecular examples are used to illustrate concepts and to show the reader how to use the techniques in chemical and biological systems. Circular Dichroism and Linear Dichroism is an easy guide to what a prospective user of CD needs to know and explains how LD is not merely an exotic technique only to be practiced by experienced spectroscopists, but may be routinely and usefully employed as an aid to molecular structure determination.
http://www.amazon.com/gp/product/019855897X/?tag=2022091-20
(This book provides an introduction to optical anisotropy ...)
This book provides an introduction to optical anisotropy (linear dichroism, LD) and optical activity (circular dichroism, CD) as techniques for the study of structures and interactions of molecules in solution. The book covers the use of these techniques for both small and large molecular systems with particular emphasis being placed on proteins and nucleic acids. CD is a well-established technique and this book aims to explain how it can be used simply and effectively for new entrants to the field as well as covering more advanced techniques for experts. LD is often seen as a rather exotic method intended only for experienced spectroscopists. This book demonstrates that it is an approach with real utility that may be used by both students and scientists from graduate level onwards to give simple answers, which are not available from any other technique, to structural and kinetic questions. Much of the emphasis is on flow orientation of samples in solution phase. The book first describes the techniques and the information they can provide; it then goes on to give specific details on how to actually implement them, including a wide range of examples showing how LD and CD can help with * protein and nucleic acid secondary structure elucidation; * analysis of the formation and rearrangements of fibrous proteins and membrane proteins; * identification of the absolute configuration of small molecules; * determination of the orientation of small molecules in anisotropic media; * assignment of transition moment polarizations; * investigation of binding strengths and geometries of ligand-macromolecule complexes; * 3-D structure determination from LD, molecular replacement and MD modeling. The advantages of combined LD/CD studies are also outlined with examples of DNA/drug complexes and protein insertion into membranes. Taken together the book represents a comprehensive text on the theory and application of LD and CD in the chemical and biological sciences.
http://www.amazon.com/gp/product/1847559026/?tag=2022091-20
Nordén, Bengt Johan Fredrik was born on May 15, 1945 in Lund, Sweden. Son of Jan Gunnar and Marit Birgitta (Strömberg) Nordén.
Bachelor of Science with honors, University Lund, 1967. Doctor of Philosophy, University Lund, 1971. Doctor of Science, University Lund, 1972.
Docent department inorganic chemistry University Lund, 1972-1979, acting professor, 1979. Chair department physical chemistry Chalmers University of Technology, Gothenbuurg, Sweden, since 1979, dean School Chemistry Sweden, 1983-1985. Advisor of science and technical The Swedish Government, 1991-1995.
Member Swedish National Science Research Council, 1986-1992, chairman chemistry section, since 1999. Adjunct member Nobel Committee Chemistry, 1996, member, since 1997, chairman, 2000-2003.
(This book provides an introduction to all those who wish ...)
(This book provides an introduction to optical anisotropy ...)
Fellow Royal Academy of Sciences (life, Göran Gustafsson Prize of Chemistry 1992, chairman Swedish national committee since 1994), Royal Society Arts and Sciences of Gothenburg (life), Royal Physiographic Society of Lund (life, Fabian Gyllenbergs Prize 1972), Royal Society Chemistry United Kingdom, Elect Chemical Society China (honorary). Member American Chemical Society, European Biophysics Chemistry, Swedish Biophysics Society (chairman since 1995), National German Academy of Sciences, Norwegian Academy of Sciences, Finnish Academy of Sciences.
Married, 1970; children: Anna, Birgitta, Catharina.