Background
Bernardino Larghi was born on February 27, 1812, in Vercelli, Italy. He was the son of Francesco Larghi and Maria de Giudice.
University of Turin, Turin, Italy
Larghi graduated in surgery from the University of Turin.
University of Genoa, Genoa, Italy
Larghi graduated in medicine from the University of Genoa in 1836.
(The book contains Larghi's work De l’extraction sous-péri...)
The book contains Larghi's work De l’extraction sous-périostée et de la reproduction des os; extraction sous-périostée des côtes en particulier.
https://www.amazon.com/Gazette-Medicale-Paris-Issues-French/dp/127227022X/?tag=2022091-20
1847
Bernardino Larghi was born on February 27, 1812, in Vercelli, Italy. He was the son of Francesco Larghi and Maria de Giudice.
Larghi graduated in surgery from the University of Turin in 1833 and in medicine from the University of Genoa in 1836.
Returning to Vercelli, Larghi established a dispensary and a small infirmary in his house and began to practice surgery privately. He was so successful that in 1838 he was asked to operate at the St. Andrea Hospital in Vercelli, first in an honorary capacity and from 1844 as a head surgeon.
The reasons for Larghi’s specific interest in subperiosteal resection require further research, but it appears that earlier biological experiments on the power of the periosteum to regenerate bone were less influential than the brilliant practical results that he obtained.
In 1845 Larghi performed a resection of the ribs - or actually, an extraction of their bony part - on a twelve-year-old boy suffering from abscess and central caries of the eighth and ninth ribs on the right side. Larghi’s subsequent works, published in the Giornale della R. Accademia medico-chirurgica di Torino, reveal the progress of his techniques for subperiosteal resection and the improvement of his surgical instruments. In May 1852 he extracted the necrotic right hemimandible of a patient, removing the condyle but leaving the articular capsula - as well as the periosteum - in position. The neoarthrosis that formed between the neocondyle of the regenerated mandible and the glenoid cavity suggested to Larghi that other soft parts might be preserved, as shown in his most noted work, Operazioni sottoperiostee e sottocassulari. After the introduction of antisepsis, subperiosteal resection developed substantially, especially through the work of L. Ollier.
(The book contains Larghi's work De l’extraction sous-péri...)
1847Costal resection involved the total removal of the bone with its periosteal covering; it required that intercostal muscles, nerves, and vessels be cut and thereby introduced the danger of hemorrhage and pneumothorax from pleural perforation. Larghi considered such resection to be more a “demolition” than a surgical procedure. He maintained that the surgeon should not destroy the ribs but, rather, restore and rebuild them, since he believed that nature “strongly thickens the periosteum and for this purpose exudes a gelatinous humor which, working its way between the periosteum and the deteriorated bony part, separates them; this humor awaits only the expulsion of the deteriorated bony part so that it can occupy the site more properly and be converted to new bone inside the case that generated it.” The surgeon’s task must, therefore, be to complete removal of the necrotic bone and to extract it from the thickened periosteal sheath.
Larghi probably was married, but nothing is known about his family.