Background
Finch, Caleb Ellicott was born on July 4, 1939 in London. Son of Benjamin F. and Faith (Stratton) Campbell. came to the United States, 1939.
(This treatment of human aging draws on biomedical researc...)
This treatment of human aging draws on biomedical research and the natural history of animals and plants to describe this natural phenomena in detail, helping the reader to understand this complex process. In the aging process of humans and many other species, the authors find some answers to why aging must exist at all. They present contemporary theories of aging and their implications for the prospect of significantly extending the human life span. The "hows" of aging, including genetic mutations, cellular degeneration, wear and tear on the body, and the gradual weakening of the body's immune system are explored carefully and fully, as are the genetic and environmental causes of aging.
http://www.amazon.com/gp/product/0716750562/?tag=2022091-20
(In Chance, Development, and Aging, two leading biological...)
In Chance, Development, and Aging, two leading biological gerontologists review and evaluate all of the available data to elucidate the respective roles played by genes and chance developmental events in determining the course of aging in individuals. The combination of genetic and external environmental influences provides only an incomplete answer. Inbred laboratory animals, for example, exhibit a wide range of life spans despite having nearly identical genes and environments. Similarly, uncovering the genetic risks for Alzheimer's disease has not enabled doctors to predict with confidence its onset and severity. This book argues that understanding chance events, specifically random variations during prenatal development, is essential for answering these questions. The book draws on the extensive research in developmental biology on random variations in form and function, while putting this research in a new context. The discussion sheds light on a range of questions, from understanding menopause to explaining why identical twins are not truly identical. The book will be invaluable for gerontologists, geneticists, developmental and reproductive biologists, physiologists, and a broad range of physicians and investigators in experimental medicine.
http://www.amazon.com/gp/product/0195133617/?tag=2022091-20
Finch, Caleb Ellicott was born on July 4, 1939 in London. Son of Benjamin F. and Faith (Stratton) Campbell. came to the United States, 1939.
Bachelor of Science, Yale University, 1961. Doctor of Philosophy, Rockefeller University, 1969.
He was the founding Director of University of Southern California"s National Institutes of Health funded Alzheimer Disease Research Center in 1984, and is currently co-Director. In 1989, the university made him one of its twelve "University Distinguished Professors". He is a full professor in Gerontology and Biological Sciences, and an adjunct professor in departments of Anthropology, Psychology, Physiology, and Neurology.
He was the Chair of the National Research Council Committee on Biodemography of Aging.
He is co-author of 520 scientific papers and four books, most recently The Biology of Human Longevity (Academic Press, 2007). He currently serves on the Scientific Advisory Board for Cure Alzheimer"s Fund.
Most recent papers are:
Kremsky I., Morgan TE, Hu, X, Li L, Finch Civil Engineering (2012) Age-related changes in glial gene expression are modified by interactions with neurons. Brain, Behav, Immunity, Special Issue on Aging, 26:797-802
Arimoto JM, Wong A, Rozovsky I, Lin Southwest, Morgan TE, Finch Civil Engineering (2013) Age increase of estrogen receptor alpha (ERα) in cortical astrocytes impairs neurotrophic support in male and female rats.
Endocrinology, 154: 2101–2113.
Davis District Attorney, Akopian G, Walsh Justice of the Peace, Sioutas C, Morgan TE, Finch Civil Engineering. (2013) Urban air pollutants reduce synaptic function of CA1 neurons via an NMDA/November pathway in vitro. J Neurochem 127:509-519. Finch Civil Engineering, Beltran-Sanchez H, Crimmins EM (2014) Uneven futures of human lifespans: reckoning the realities of climate change with predictions from the Gompertz model.
Gerontology 60:183-8.
Finch Civil Engineering, Austad Civil Engineering. 2015. Is Alzheimer disease uniquely human? Commentary, Neurobiol Aging 36:553-555
Cacciottolo M, Christensen A, Moser A, Liu J, Pike CJ, Sullivan Prime Minister, Morgan TE, Finch Civil Engineering. The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer ‘s Disease of humans and mice.
Neurobiol Aging, in press
(In Chance, Development, and Aging, two leading biological...)
(This treatment of human aging draws on biomedical researc...)
( Featuring extensive references, updated for this paperb...)
(Will be shipped from US. Used books may not include compa...)
HIN research grantee, since 1972. Recipient Brookdale award, 1985, Allied Signal Inc. award Achievement in biomedical Aging, 1988, Research award Alzheimer's Association Los Angeles, 1989, Cherkin award University of California at Los Angeles, 1991, American Aging Association award, 1994, Sandoz Premier prize International Association Gerontology, 1995. Fellow American Association for the Advancement of Science, Gerontological Society American (chairman biology section 1992-1993, Robert W. Kleemeier award 1984).
Member Neurosci. Society, Endocrine Society, Neuroendocrine Society, Psychoneuroendocrine Society, Iron Mountain String Band (fiddler since 1963).
Married Doris Nossamen, October 11, 1975. Stepsons: Michael, Alec Tsongas.