Catherine was instrumental in the spread of the Reformation in the Margraviate of Brandenburg. She had several outbuildings in Küstrin and a kitchen garden. Catherine settled Dutch religious refugees in Dębno, who started a vibrant clothi-making industry.
She built a school and a church and in 1562, Dębno was granted a city charter.
Catherine, who was described as very popular, was known by the population as Mother Kate. She founded the first pharmacy in Ośno Lubuskie and built another in Küstrin from which she provided the poor with free medicine.
Catherine built numerous farms and dairies, which she administered herself and she also sold the harvest herself. Catherine died in 1574.
Her grave was discovered in 1999 in the ruins of the parish church in Küstrin by archaeologists from Szczecin.
The Katharinenstraße ("Catherine Street") in Berlin-Halensee is named after her. Elisabeth (1540–1578)
married in 1558 Margrave George Frederick I of Brandenburg-Ansbach (1539-1603)
married in Elector in 1570 Joachim Frederick of Brandenburg (1546-1608).