A career educator, Amoah began teaching English in Ghana in 1967. She also taught in Lesotho, Swaziland (where she lectured part-time at the University of Swaziland) and Botswana. She also served as Ghana"s ambassador to Cuba from 2006 to 2009.
In 2000, she left the education field and returned to Ghana to enter politics. On 13 June 2015, Amoah won the Asutifi South Constituency New Patriotic Party parliamentary primaries to represent the party again in the Ghanaian general election in 2016.
Amoah was the member of parliament for the Asutifi South Constituency from January 2001 to January 2005.
