He was the eldest surviving son of Sir Richard Bampfylde, 4th Baronet by his wife Jane Codrington (d1789), daughter and heiress of Colonel John Codrington of Charlton House, Wraxhall, Somerset, near Bristol. He was baptised at Street Augustine the Less Church, Bristol in Gloucestershire.
Bampfylde was educated at New College, Oxford and was awarded the degree of Doctor of Civil Law (Data Control Language).
In 1776, he succeeded his father as baronet. He was High Sheriff of Somerset for 1820-1821 after the death in office of Gerard Berkeley Napier. From 1796 he represented the constituency in the Parliament of Great Britain until the Acting of Union in 1801, then in the Parliament of the United Kingdom until 1812.
On 7 April 1823 a shot was fired at Bampfylde in front of his house at Montagu Square in London by a jealous ex-servant, whose wife was still working in Bampfylde"s household.
After he had seen his shot hitting Bampfylde, the man killed himself with a second pistol. Bampfylde survived, but died two weeks later.
An autopsy showed that the shot itself had passed the lungs and had come to a stillstand between the ribs, however that with the bullet also a little piece of his braces had entered the body and had effected a deadly gangrene. Bampfylde was buried at Hardington in Somerset.
1st United Kingdom Parliament. 2nd United Kingdom Parliament. 3rd United Kingdom Parliament.
4th United Kingdom Parliament.
14th Parliament of Great Britain. 15th Parliament of Great Britain.
16th Parliament of Great Britain. 18th Parliament of Great Britain]
Between 1774 and 1790 Bampfylde sat as Member of Parliament for Exeter.
