Charles V was born on 24th February, 1500, in Ghent, Flanders, which is now known as Belgium. His father was Philip who was the Fair of Hapsburg as well as known as the Lord of the Netherlands. His mother Joanna was the Mad of Castile and Aragon. After the death of his father, he was raised by his aunt, the reagent of Netherlands, Margaret of Austria. His maternal grandfather was Ferdinand II of Aragon and Isabella I, the Roman Catholic king and queen of Spain. His paternal grandfather was the emperor Maximilian I and grandmother was Mary, the duchess of Burgundy. He also had a brother whose name was given on his maternal grandfather as Ferdinand.