Christiane was the eldest child of Duke Charles Louis Frederick of Mecklenburg and Princess Elisabeth Albertine of Saxe-Hildburghausen. She met Thomas Nugent there in 1767 and she later became a canoness in Herford Abbey (whilst remaining in Neustrelitz). On 13 January 1766 she was made a Dame, 1st Class of the Order of Street Catherine.
She died shortly after Adolphus and was buried in the royal crypt at Mirow.
Fritz Reuter portrayed her as Prinzess Christel or Christel-Swester in his Dörchläuchting (1866). Grete Grewolls: Wer war wer in Mecklenburg und Vorpommern.
Das Personenlexikon. Hinstorff Verlag, Rostock 2011,, p.