Very little is known about van den Berghe and he was only rediscovered as an independent artist in the 1950s when some works formerly attributed to other artists were reattributed to him. He may have trained under Ambrosius Bosschaert. In 1619 he registered in the Guild of Saint Luke in Middelburg and in 1621 he was dean of the Guild.
He bought a house in MIddelburg in 1621 which he still owned in 1628.
Johannes Goedaert was his pupil.