Career
He was drafted in the fourth round of the 1980 Major League Baseball Draft by the Texas Rangers. On December 5, 1988, he was traded by the Texas Rangers with Paul Kilgus, Mitch Williams, Steve Wilson, and minor leaguers Luis Benitez and Pablo Delgado to the Chicago Cubs for Rafael Palmeiro, Jamie Moyer, and Drew Hall. After two seasons with the Cubs, Wilkerson played with the Pittsburgh Pirates and the Kansas City Royals.
After ending his playing career, Wilkerson coached in the Royals and Pirates organizations.
He was the manager of the Tarrant County Blue Thunder of the independent Continental Baseball League before the team folded after the 2008 season.