Career
He sits in the Argentine Senate representing San Luis Province in the majority block of the Front for Victory. Pérsico qualified as a civil engineer in 1988 from the National University of Córdoba and began working for the provincial government in 1989. In 1996 he joined the municipality of San Luis as Director of Basic Municipal Services, then as Subsecretary of Public Works and Services.
From September 2000 until November 2003 he served as Secretary of Public Works and Services.
On 9 November 2003, Pérsico was elected as Mayor of San Luis in an election which took place in the streets rather than official polling places, organised by the outgoing city government of Carlos Ponce. There followed a long Supreme Court battle with Governor Rodríguez Saá over the election.
Eventually the court ruled in favour of Pérsico in February 2005. In 2005 Pérsico was elected as a national Senator.
He had prepared to stand for the governorship in 2007 but stood down as a candidate ahead of the election.