Bachelor, Brandeis University, 1966. Master of Arts, Brandeis University, 1971. Doctor of Philosophy in Molecular Biology, Massachusetts Institute of Technology, 1973.
Member of staff division biological research, Ontario (Canada) Cancer Institute, 1973-1975; assistant professor department medical biophysics, U. Toronto, 1973-1975; fellow, Jane Coffin Children's Foundation, Massachusetts Institute of Technology, Boston, 1971-1973; assistant professor biology, Massachusetts Institute of Technology, Boston, 1975-1978; associate professor, Massachusetts Institute of Technology, Boston, 1978-1985; professor, Massachusetts Institute of Technology, Boston, since 1985. Associate in neurology and genetics, Massachusetts General Hospital, Boston, since 1979. Member of advisory board mammalian genetics study section National Institutes of Health, 1980-1984, Hereditary Disease Foundation, since 1980, National Neurofibromatosis Foundation, since 1982, tourette's Syndrome Association, since 1983, Eleanor Roosevelt Institute Cancer Research, since 1991, Muscular Dystrophy Association, since 1992, National Center for Human Genome Research, since 1992.
Fellow American Association for the Advancement of Science, American Academy Microbiology. Member NAS-Institute Medicine.