Background
Lewis, David Francis Victor was born on January 27, 1949 in Barnet, England. Son of Francis David and Minnie Ethel Oliver (Read) Lewis.
(This guide to the structure, function and mechanism of th...)
This guide to the structure, function and mechanism of the cytochromes P450 focuses on the role of P450s in xenobiotic metabolism and toxicity. Colour illustrations show how modelling of P450s can rationalize their substrate specificity for the metabolism of both endogenous and exogenous chemicals.
http://www.amazon.com/gp/product/0748404430/?tag=2022091-20
(Cytochromes are coloured iron-containing proteins that tr...)
Cytochromes are coloured iron-containing proteins that transfer electrons during cellular respiration and photosynthesis. The Cytochrome P450 family of enzymes catalyze reactions whereby water-insoluble drugs or metabolites, that would otherwise reach toxic levels in cell membranes, are rendered suitably water-soluble to leave the cell and be excreted in the urine. This reference reviews the current status of the P450 field in terms of our present knowledge and understanding of the enzymes' structure and function, including their multiplicity of forms, diversity of substrates and selectivity. This is brought together with the latest research topics - including pharmacogenetics, regulation, human DMEs, toxicity screening and molecule modelling - to provide a fast-track approach for those new to the field.
http://www.amazon.com/gp/product/0748408975/?tag=2022091-20
Lewis, David Francis Victor was born on January 27, 1949 in Barnet, England. Son of Francis David and Minnie Ethel Oliver (Read) Lewis.
Bachelor of Science in Chemistry, University Bath, England, 1971. Master of Science in Spectroscopy, University Surrey, England, 1972. Doctor of Philosophy in Chemistry, University Surrey, England, 1982.
Doctor of Science, University Bath, England, 2003.
Teacher St. Peters and Merrow Grange School, Guildford, 1973-1974, Guildford County School, 1979-1987. Research fellow University Surrey, Guildford, 1987-1997, senior research fellow, 1997-1999, reader, 1999—2002, professor, since 2003.
(This guide to the structure, function and mechanism of th...)
(Cytochromes are coloured iron-containing proteins that tr...)
Member International Society for the Study Xenobiotics, Society of Chemists in Industry, New York Academy of Sciences.