Background
Latchman, David Seymour was born on January 22, 1956 in London. Son of Emanuel and Ella (Wohl) Latchman.
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book
Eukaryotic Transcription Factors, Fourth Edition
(Now in two-colour throughout, the fourth edition of Eukar...)
Now in two-colour throughout, the fourth edition of Eukaryotic Transcription Factors has been completely rewritten and restructured to take into account the tremendous advances in our understanding of transcription factors and the mechanisms by which they act. Considerable emphasis has been given to the interaction between transcription factors and chromatin structure. Also included is an entirely new section on the mediator complex and expansion of the space devoted to co-activators and co-repressors. This book is essential reading for all those who wish to understand the impact of molecular biology on medicine, whatever their speciality. * Major families of eukaryotic transcription factors described * Mechanisms of gene activation and repression analysed * Structure-function relationships indicated * Interaction between transcription factors and chromatin structure described * Roles in inducible and cell type-specific gene expression * Roles in development, differentiation and human diseases including cancer * Methods of study in vitro and in vivo
http://www.amazon.com/gp/product/0124371787/?tag=2022091-20
Eukaryotic Transcription Factors, Fifth Edition
(Transcription, or the process by which DNA produces RNA, ...)
Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. • Potential of transcription factors as therapeutic targets in human disease • Importance of histone modifications • Use of genome-based sequence analysis and high-throughput methods • Applications of the chromatin immunoprecipitation (ChIP) assay • Transcriptional elongation • Regulation by post-translational modifications • Regulatory networks and bioinformatics
http://www.amazon.com/gp/product/0123739837/?tag=2022091-20
Gene Regulation (Advanced Texts) by David Latchman (2005-07-25)
http://www.amazon.com/gp/product/B01JXS73UY/?tag=2022091-20
Eukaryotic Transcription Factors, Fourth Edition by David S. Latchman (2003-12-17)
http://www.amazon.com/gp/product/B01FGO5G8K/?tag=2022091-20
Gene Regulation (Advanced Texts)
( Gene regulation is an essential process in the developm...)
Gene regulation is an essential process in the development and maintenance of a healthy body, and as such, is a central focus in both basic science and medical research. Gene Regulation, Fifth Edition provides the student and researcher with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview.
http://www.amazon.com/gp/product/0415365104/?tag=2022091-20
Gene Regulation (Advanced Texts) by David Latchman (2005-06-16)
http://www.amazon.com/gp/product/B01K0VATJU/?tag=2022091-20
Gene Regulation: A Eukaryotic Perspective by David S. Latchman (2008-06-13)
http://www.amazon.com/gp/product/B01FJ1N9UW/?tag=2022091-20
David Seymour Latchman
Edit Profileeducator molecular pathologist
Education
Bachelor, Cambridge U., 1978; Master of Arts, Cambridge U., 1981; Doctor of Philosophy, Cambridge U., 1981; Doctor of Science, London U., 1994.
Career
Postdoctoral research fellow Imperial College, London U., 1981-1984; lecturer, reader, University College London, 1984-1992; professor, head department molecular pathology, University College London, since 1992; director, Windeyer Institute Medical Sciences, London, since 1996. Consultant Oncogne Science, New York City, since 1995. Member medical committee Parkinson's DiseaseSoc., London, since 1994.
Achievements
Works
book
-
Eukaryotic Transcription Factors, Fourth Edition
(Now in two-colour throughout, the fourth edition of Eukar...)
-
Gene Regulation (Advanced Texts)
( Gene regulation is an essential process in the developm...)
-
Eukaryotic Transcription Factors, Fifth Edition
(Transcription, or the process by which DNA produces RNA, ...)
- Eukaryotic Transcription Factors (4th) Fourth Edition
- Gene Regulation (Advanced Texts) by David Latchman (2005-07-25)
- Eukaryotic Transcription Factors, Fourth Edition by David S. Latchman (2003-12-17)
- Gene Regulation (Advanced Texts) by David Latchman (2005-06-16)
- Gene Regulation: A Eukaryotic Perspective by David S. Latchman (2008-06-13)
-
Eukaryotic Transcription Factors, Fourth Edition
Membership
Member American Association for the Advancement of Science, American Association Microbiology, New York Academy Sciences.
