Dean Kamen was born on April 5, 1951, in Rockville Centre, New York, the United States, to Jack and Evelyn Kamen. His father was a renowned illustrator who worked for Mad, Weird Science, and other EC Comics publications. His mother worked as a teacher. Dean had two brothers, Mitch and Barton, and a sister, Terri. Barton Kamen, who was a clinical professor of pediatrics and pharmacology, passed away on 27 September 2012 at the age of 63.