Lopez has three older brothers, Steven and Mark who are also Olympians and Jean Lopez who coaches Lopez and her other two brothers. Her family is originally from Nicaragua. She graduated from Kempner High School in 2002, and is a student at the University of Houston–Downtown.
On August 10, 2013 Lopez married strength and conditioning coach of the National Basketball Association"s Houston Rockets Joe Rogowski.
She represented the United States at the 2008 Olympics in Beijing, where she won a bronze medal. In 2005, Diana and her brothers made history by becoming the first three siblings, in any sport, to win World titles at the same event, when they did so at the 2005 World Taekwondo Championships in Madrid, Spain and in 2008, Diana and her brothers made history again by becoming only the second set of three or more siblings to all qualify for the Olympics.
