Doctor of Philosophy, Ecole Normale Supérieure, Paris, France, 1982.
Sylvain worked as an independent journalist for Le Journal du dimanche, then as a corporate journalist managing sponsorships in the steel industry at the Usinor group. Sylvain began writing in 1993 during her first stay in Japan. The city of Tokyo provided the setting for her first novel Baka ! ("idiot" in Japanese).
Following this, Vox, in 2000, and Cobra introduce a trio of officers of the Brigade criminelle (French criminal investigators) lead by the commander Alexandre Bruce. Vox features a serial killer who dreams of downloading his mind into a machine.She was awarded the Sang d'Encre prize in 2000 for the novel Vox, and the Michel Lebrun prize en 2001 for Strad, which involves performers who use their body as a means of expression. In 2004, she started the Ingrid et Lola series centering on the unofficial investigations of the American masseuse Ingrid Diesel and the retired commissioner Lola Jost.
These stories include a mix of traditional crime fiction and humor. She was presented with the Elle magazine Grand Prix des Lectrices in 2005 for Passage du Désir (translated into English as Dark Angel
In 2007, the Sylvain rewrote her first book, Baka !, further developing the character of Louise Morvan. The detective later played a major role in Sylvain's La Nuit de Geronimo, a novel which intertwines dark family secrets, unethical research in molecular biology and GMOs.
Her novel Sœurs de Sang centers around "victim art". In the short story compilation Régals du Japon et d'ailleurs, Sylvain temporarily moved away from crime fiction, reminiscing on the gastronomic experiences of her youth and her travels. In 2011 Sylvain contributed a story about Japanese passion for football to the Contrebandiers firm's collection Les Hommes en noir.
Also that year her story Guerre sale was selected by the staff of LIRE magazine as the best French crime novel of 2011. In 2012, she published the novel Le Roi Lézard, a rewrite of Travestis (1998) which features Jim Morrison, the lead singer of The Doors. I,In 2013, Sylvain contributed to the short story collection Femmes en colère along with Didier Daeninckx, Marc Villard and Marcus Malte.
Also in 2013, she released Ombres et soleil, a direct sequel of Guerre sale. Sylvain's novels have all been published by Éditions Viviane Hamy, in the Chemins Nocturnes collection. Her stories have been translated in almost a dozen languages, including Russian and Japanese.
Married Anne Granier. Children: Felix, Gaspar.