Background
Bers, Donald Martin was born on December 13, 1953 in New York City. Son of Harold Theodore and Penny (Wall) Bers.
(How is the heartbeat generated? What controls the strengt...)
How is the heartbeat generated? What controls the strength of contraction of heart muscle? What are the links between cardiac structure and function? How does our understanding of skeletal and smooth muscle and non-muscle cells influence our thinking about force development in the heart? Are there important species differences in how contraction is regulated in the heart? How do the new molecular data fit together in understanding the heart beat? What goes wrong in ischemia, hypertrophy, and heart failure? This book paints a modern 'portrait' of how the heart works and in this picture the author shows a close-up of the structural, biochemical, and physiological links between excitation and contraction. The author takes the reader through a series of important, interrelated topics with great clarity and continuity and also includes many useful illustrations and tables. The book starts by considering the cellular structures involved in excitation-contraction coupling and then described the characteristics of the myofilaments as the end effector of excitation-contraction coupling. A general scheme of calcium regulation is described and the possible sources and sinks of calcium are discussed in simple, but quantitative terms. The cardiac action potential and its many underlying currents are reviewed. Then the characteristics of some key calcium transport systems (calcium channels, sodium/calcium exchange and SR calcium uptake and release) are discussed in detail. This is then built into a more integrated picture of calcium regulation in succeeding chapters by detailed discussions of excitation-calcium coupling mechanisms (in skeletal, cardiac, and smooth muscle), the interplay between calcium regulatory processes, and finally mechanisms of cardiac inotropy, calcium overload, and dysfunction (e.g., ischemia, hypertrophy, and heart failure). Excitation-Contraction Coupling and Cardiac Contractile Force &endash; Second Edition is an invaluable source of information for anyone who is interested in how the heart beat is controlled and especially suited for students of the cardiovascular system at all levels from medical/graduate students through senior investigators in related fields.
http://www.amazon.com/gp/product/0792371585/?tag=2022091-20
Bers, Donald Martin was born on December 13, 1953 in New York City. Son of Harold Theodore and Penny (Wall) Bers.
Bachelor, U. Colorado, 1974; Doctor of Philosophy, University of California at Los Angeles, 1978.
Postdoctoral research fellow, University of California at Los Angeles, 1978-1979; assistant research physiologist, University of California at Los Angeles, 1980-1982; adjunct assistant professor, University of California at Los Angeles, 1981-1987; postdoctoral research fellow, Edinburgh (Scotland) U., 1979-1980; assistant professor, University of California, Riverside, 1982-1986; associate professor, University of California, Riverside, 1986-1989; professor, University of California, Riverside, 1989-1992; divisional dean, director biomedical science program, University of California, Riverside, 1991-1992; professor, department chairman physiology, Loyola University, Chicago, since 1992.
(How is the heartbeat generated? What controls the strengt...)
Board of directors American Heart Association, Riverside, 1985-1992, president, 1989-1991. Member American Association for the Advancement of Science, American Physiological Society, Biophysics Society (member county, member Executive Board), International Society Heart Research, Society General Physiology. M C.
Married Kathryn Eileen Hammond, July 17, 1976. Children: Brian Alexander, Rebecca Annual.