May Best was orphaned at an early age and raised by family in Boston. As a faculty wife she became fully involved in many organizations they supported, one of the most important being the Imperial Order of the Daughters of the Empire. She served a term as the first municipal regent.
She was aggressively involved in women's issues revolving around education and the roles of women. May Sexton is mainly remembered in Canadian history through her involvement in the war effort. The Local Council of Women of Halifax spearheaded an intense war effort from that city and the whole province and Sexton was a leading force.