Career
Club career
Domínguez began his career with Vélez Sársfield in 1996. He remained at Vélez until 2002, when he was loaned out to Olimpo de Bahía Blanca. At Olimpo, Domínguez had a stellar season.
He then joined Racing Club where he suffered a major injury.
The following season he joined Independiente de Avellaneda and quickly recovered his form. In 2006, he joined Colombian power Independiente Medellín and was one of the clubs most important players.
After two seasons in Colombia, Domínguez returned to Argentina to play for Huracán during the 2008 Clausura where he established himself as an important first team player. On July 8, 2008, the Los Angeles Galaxy (Major League Soccer) announced that Eduardo Domínguez had joined the team
Dominguez was not expected to play for the Galaxy until July 19, 2008 when the Galaxy face the New York Red Bulls.
This was due to his pending work visa and for the transfer window to open up on July 15, 2008. In January, 2009 it was announced that the Los Angeles Galaxy defender Eduardo Dominguez had returned to his previous team, Club Atlético Huracán, signing a one-and-a-half year deal with "El Globo" according to multiple media reports out of South America in the past week. On the Argentine club’s website, they herald his return, calling Dominguez the first big reinforcement of the current transfer window.