Career
He belonged to the recusant family of Mayhew or Mayow of Winton, near Salisbury, Wiltshire. Moving to Rome, he there continued his studies until his ordination, after which he left for the English mission in 1595. He was professed by Dom Sigelbert Buckley, the sole survivor of the English congregation, in his cell at the Gatehouse prison, Westminster, on 21 November 1607, with Robert Sadler.
Under these two new members the English congregation began to revive.
Becoming affiliated with the Spanish congregation in 1612, it was given an equal share in Saint Lawrence"s monastery at Dieulwart, Lorraine, henceforth the centre of the English congregation. Retiring from the English mission in 1613, Mayhew took up his residence at Dieulwart, where he filled the office of prior from 1613 to 1620.
The union of the three congregations engaged on the English missions had for some time been canvassed, in 1617 Mayhew was appointed one of the nine definitors to bring this about. From 1623 until his death he acted as vicar to the nuns at Cambrai.
His remains lie in the parish church at Street-Vedast.