Eiichi Makino graduated from the Law College of the Imperial University of Tokyo in 1903. He went to Germany, England and Italy to study laws in 1910. He studied the criminal law of "the progressive school" under Franz von Liszt at Berlin University (Friedrich-Wilhelms-Universitat zu Berlin).
After returning to Japan, Eiichi Makino served as professor at the Imperial University of Tokyo from 1913 to 1938.
Eiichi Makino advocated criminal law theory based on subjectivism, the deterrent theory of punishment and the correctional theory of punishment and prompted improvements in prison and jail administration.
Eiichi Makino was selected as a member of the House of Peers in 1946.