In 1960 Emma Sarkisyan graduated from the Moscow State Conservatory. P.I. Tchaikovsky (class prof. A.L. Dolivo).
After graduation, Emma Sarkisyan was accepted to the opera troupe of the Moscow Academic Musical Theater named after K.S. Stanislavsky and Vl.I. Nemirovich-Danchenko, where she played leading roles such as Olga ("Eugene Onegin" by P. Tchaikovsky), Rozina ("Barber of Seville" by J. Rossini), Carmen ("Carmen" by J. Bizet).
Since 1991, since the founding of the New Opera, Emma Sargsyan began working in this theater. Here her repertoire included the following parts: Naina ("Ruslan and Lyudmila" by M. Glinka), Nanny ("Demon" by A. Rubinstein) and others.
In 2007, Emma Sarkisyan took part in the Salzburg Festival, performing the part of the Nanny (Eugene Onegin, conductor Daniel Barenboim). In 2008, she sang the part of Buryi ("Enufa" by L. Janacek) at the National Theater of Mannheim.