She earned her degree in Pharmaceutical Biochemistry from the in 1982. She has a Doctor of Philosophy in Biochemistry and Clinical Toxicology, Metabolic Regulation, Environmental contaminants and biochemical effects, Neurochemistry and Experimental Hematology. In February 1985 she studied at the United States Oak Ridge National Laboratory.
In politics, she worked for the Partido Popular (Partido Popular (Popular Party)) and was alcadesa and councillor in Requena for 9 years (1995-2003).
Margin was a researcher at the Centre for Energy Environment and Technology, (1982-1985), a Member of the Nuclear Energy Board (1989-1991) and Coordinatora for the Internal Dosimetry Group of the Spanish Society for Radiological Protection. She held various positions in Valencia as President of the Valencian Federation of Municipalities and Provinces (FVMP), (1999-2003), Director General of Irrigation and Agricultural Infrastructure (1999-2003), Executive member of the provincial People"s Party, Regional board member and secretary of local politics and deputy member of the Corts Valencianes Parliament of Valencia, during the Elections to the Corts Valencianes, 2007 and Elections to the Corts Valencianes, 2011,(2007-2011).
