Career
Margáin served as municipal president (mayor) of San Pedro from 1994 to 1997. Later, from 1997 to 1999, he served in the cabinet of Governor Fernando Canales. In 2000 he was elected to served in the Senate of Mexico.
He was municipal president (mayor) of San Pedro Garza García again from 2006 to 2009.
Son of Ricardo Margain Zozaya who was one of the main politicians in Nuevo León State in 60"s and 70"son Fernando Margáin is married to Alejandra Sada de Margáin.
In March of 2015, he announced his intention of running for municipal president (mayor) of San Pedro Garza García again, this time as a candidate for the Humanist Party.