Born in Acquarica del Capo, Lecce Simone started his career winning the Castrocaro Music Festival in 1972. In 1974 he entered the competition at the with the song "Fiume grande", obtaining his first success in the Italian hit parade. "Fiume grande" also had a significant international success in its French and Spanish version (under the titles, respectively, "Je ne comprends plus rien" and "Río Grande").
In 1976 Simone got his main success in Italy with the song "Tu e così sia", which peaked fourth in the hit parade.
In the following years Simone grew his international popularity, especially in Latin America, where he gradually focused his career.