Career
He was a pupil, and later Prosector under Karl Kaspar von Siebold (1736–1807) at Würzburg. Later Hesselbach was a lecturer at Würzburg, where one of his students was Konrad Johann Martin Langenbeck (1776–1851). As a surgeon, Hesselbach is best known for his work with hernia operations.
He was the first to describe a handful of anatomical structures, such as the cribriform fascia (Hesselbach"s fascia), interfoveolar ligament (Hesselbach"s ligament) and the inguinal triangle (Hesselbach"s triangle).