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Frederick Sanger

Research biochemist

Frederick Sanger, British biochemist. Achievements include discovery of the complete amino acid sequence of the two polypeptide chains of insulin; development of several methods to sequence the nucleic acids DNA and Ribonucleic acid including methods reading DNA using special bases called chain terminators, the use of very thin gel systems and the adaptation of efficient cloning methods to produce both DNA strands and the whole-genome shotgun.

Background

Sanger, Frederick was born on August 13, 1918 in Rendcomb, Gloucestershire, England. Son of Frederick and Cicely Sanger.

Education

Bachelor, St. John's College, University Cambridge, 1940. Doctor of Philosophy, St. John's College, University Cambridge, 1943. Doctor of Science (honorary), Leicester University, 1968.

Doctor of Science (honorary), Oxford University, 1970. Doctor of Science (honorary), Strasbourg University, 1970.

Career

Beit memorial medical research fellow University Cambridge, 1944-1951, research scientist, department biochemistry, 1944-1961, research scientist, division head Medical Research Council Laboratory Molecular Biology, 1962-1983.

Achievements

  • Achievements include discovery of the complete amino acid sequence of the two polypeptide chains of insulin. Development of several methods to sequence the nucleic acids DNA and Ribonucleic acid including methods reading DNA using special bases called chain terminators, the use of very thin gel systems and the adaptation of efficient cloning methods to produce both DNA strands and the whole-genome shotgun.

Works

  • Other Work

    • Contributor articles to professional journals.

Membership

Scientific Staff, Medical Research Council 1951-1983. American Academy, of Arts and Sciences since 1958. American Society of Biological Chemists, Japanese Biochemical Society.

Asociacion Quimica de Argentina. Academy, of Science of Argentina and Brazil, World Academy, of Arts and Science, Russell Committee against Chemical Weapons since 1981.

Interests

  • Other Interests

    Boating, gardening.

Connections

Married Margaret Joan Howe, 1940. Children: Robin, Peter Frederick, Sally Joan.

father:
Frederick Sanger

mother:
Cicely Sanger

spouse:
Margaret Joan Howe

child:
Robin Sanger

child:
Peter Frederick Sanger

child:
Sally Joan Sanger