Bachelor, Amherst College, 1962. Master of Science, Yale University, 1964. Doctor of Philosophy in Genetics, Yale University, 1965.
Doctor of Science (honorary), Amherst College, 1982.
Postdoctoral fellow National Science Foundation, National Institutes of Health, 1965-1966, United States Public Health Service, National Institutes of Health, 1966-1967. Instructor National Institutes of Health Health Graduate Program, 1966, Cold Spring Harbor Summer Program, 1970-1987. Assistant professor genetics Cornell University, 1967-1971, associate professor genetics, 1971-1976, professor genetics New York City, 1976-1979, professor biochemistry, 1979-1982.
Professor molecular genetics Massachusetts Institute of Technology, since 1982. Professor genetics American Cancer Society Whitehead Institute biomedical Research, since 1982. Director Whitehead Institute biomedical Research, since 1990.
Organizer International Conference on Molecular Biology of Yeast, Cold Spring Harbor, 1975. Chairman advisory group Virology and Cell Biology American Cancer Society, 1976-1977. Co-chairman Gordon Conference Biological Regulations Mechanisms, 1977.
Member genetics study section National Institutes of Health, 1979-1984. Member visiting committee Carnegie Institute, since 1983. Director Whitehead Institute biomedical Research, since 1990.
Member National Academy of Sciences, Academy Arts and Sciences, Genetics Society of America (secretary 1977-1980, vice president 1986-1987, president 1988-1989).
Married Rosalie Pamela Lewis, June 15, 1961. Children: Julia, Jennifer.