Career
Born in Katerini, Zisopoulos began playing football for PAOK F.C., signing a professional contract in December 2004. He would only make 17 league appearances for the club before moving to Levadiakos F.C. in August 2005. He joined Greek second division side Panthrakikos F.C. in August 2010.
On 6 June 2013 Zisopoulos signed for Asteras.