Artusi fiercely condemned the new musical style developing around 1600, the innovations of which defined the early Baroque era. He was also a scholar and cleric at the Congregation San Salvatore at Bologna, and remained throughout his life devoted to his teacher Gioseffo Zarlino (the principal music theorist of the late sixteenth century). When Vincenzo Galilei first attacked Zarlino in the Dialogo of 1581, it provoked Artusi to defend his teacher and the style he represented.
In 1600 and 1603 Artusi attacked the "crudities" and "license" shown in the works of a composer he initially refused to name (it was Claudio Monteverdi). Monteverdi replied in the introduction to his fifth book of madrigals (1605) with his discussion of the division of musical practice into two streams: what he called prima pratica, and seconda pratica: prima pratica being the previous polyphonic ideal of the sixteenth century, with flowing counterpoint, prepared dissonance, and equality of voices; and seconda pratica being the new style of monody and accompanied recitative, which emphasized soprano and bass voices, and in addition showed the beginnings of conscious functional tonality.
He recognized that there could be more dissonance than consonance in a developed piece of counterpoint, and he attempted to enumerate the reasons and uses for the dissonances, for example as settings of words expressing sorrow, pain, longing, terror. Ironically, the usage of Monteverdi in the seconda pratica largely agreed with his book, at least conceptually; the differences between Monteverdi's music and Artusi's theory were in the importance of the different voices, and the exact intervals used in shaping the melodic line.