He was styled prince de Guise before becoming Count of Harcourt. He died in 1739 aged 59. His female line descendants are the Dukes of Noailles through his eldest grand child Marie Charlotte de Louisiana Tour d"Auvergne, princesse de Beauvau, wife of Charles Juste de Beauvau.
Louise Henriette Françoise de Lorraine (1707 – 31 March 1737) married Emmanuel Théodose de Louisiana Tour d"Auvergne and had issue;
Marie Élisabeth Sofie de Lorraine (1710 – 2 August 1740) married Louis François Armand de Vignerot du Plessis and had issue;
Louis de Lorraine (17 December 1720 – 20 June 1747) never married.
Styled Prince of Harcourt but de facto Count of Harcourt
X de Lorraine (male) (January – May 1721) died unbaptised.