Background
Gabra, Hani was born on January 15, 1963 in Cairo, Egypt. Son of Gamal Saber Gabra and Samira Daoud Iskander-Gabra.
Gabra, Hani was born on January 15, 1963 in Cairo, Egypt. Son of Gamal Saber Gabra and Samira Daoud Iskander-Gabra.
Hani studied Medicine at the University of Glasgow and graduated with a Bachelor of Science (Honours) in Molecular Biology and Bachelor of Medicine Bachelor of Surgery in 1987. After obtaining Membership of the Royal College of Physicians(United Kingdom) in 1990, he undertook an Master of Science in Clinical Oncology and a Doctor of Philosophy in Molecular Oncology from the University of Edinburgh. He then completed his specialist training in Cancer Medicine in Edinburgh and was CRUK Clinical Scientist and Consultant Medical Oncologist at the CRUK Edinburgh Medical Oncology Unit from 1998-2003 when he came to Imperial as Chair in Medical Oncology.
He is Director of the Ovarian Cancer Action Research Centre at Imperial College. Gabra is Professor of Medical Oncology and Deputy Head of the Division of Cancer (Clinical) at Imperial College London. He is also Head of the Molecular Therapeutics Unit and Director of the Ovarian Cancer Action Research Centre at Imperial College.
Within Imperial College Healthcare National Health Service Trust, he is Head of the Medical Oncology Service, Lead Clinician for Cancer Clinical Trials and Honorary Consultant Medical Oncologist.
He is a Fellow of the Royal College of Physicians of Edinburgh and London. As well as leading the Ovarian Cancer Programme at Imperial, his laboratory is involved in trying to understand the role of tumour suppressor genes in ovarian cancer, particularly how OPCML regulates networks of receptor tyrosine kinases and how WWOX acts to regulate taxane sensitivity.
His clinical / translational interests relate to the understanding of platinum resistance in ovarian cancer, and he has developed several molecular targets whose inhibition can reverse platinum resistance from laboratory to clinic. Such targets include AKT, MTOR, HDAC4, STAT1 and the Folate receptors.
He is President of the European Translational Ovarian Cancer Network (EUTROC), a multinational group that undertakes science in ovarian cancer clinical trials, principally in the context of complex phase II clinical trials.
He currently sits on the CRUK CTAAC funding committee for the United Kingdom and the INCa Scientific Evaluation Committee, Institut National Du Cancer of France. He is on the Editorial Boards of several journals including Gynecologic Oncology and the European Journal of Cancer. Hani"s research is principally funded by Ovarian Cancer Action, the national ovarian cancer charity.
He is also funded by CRUK and European Union FP7 as well as translational / clinical trials funding from pharmaceutical collaborations.
Fellow: Royal College Physicians, Royal College Physicians Edinburgh. Member: British Gyn. Cancer Society (correspondent), Association Physicians Great Britain and Ireland (correspondent), British Association Cancer Research (correspondent), European Society Medical Oncology (correspondent), Association Cancer Physicians United Kingdom (correspondent), American Association Cancer Research (correspondent).
Married Laura Elizabeth Lee, March 28, 1992. Children: David Angus, Katie Isis, Jonathan Alexander.